In the first half, author Nick Redfern joined George Knapp to discuss his years-long research into monsters and cryptozoology, and the latest on his journey to discover the truth about werewolves, lake monsters, giant cats, ghostly devil dogs, and other creatures. Redfern began by pointing out that the only commonality among all of these strange creatures is that "they are 100% elusive." None have ever been caught, and this is what keeps them mysterious. He said that many paranormal creature sightings seem to occur near or at ancient sites and burial grounds, including so-called "phantom back dogs" which plague the UK and which Arthur Conan Doyle used as the inspiration for his story of the "Hound of the Baskervilles."

Redfern’s newest book examines government files on possible UFO abductions. He said that the US and British governments began monitoring UFO witnesses in the 1950s, specifically the "contactees," who claimed to be visited by human-looking aliens. The interest was kindled since the majority claimed that the aliens had a communist-type government and the authorities were worried about the fact this would have on their readers and those who attended their lectures. He has also interviewed abductees who have told him that they have been visited by government agents who seem to want to give them "some insight as to why this is being done."

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Christopher White, professor of religion at Vassar College, points to ways that both spiritual practices and scientific speculation about multiverses and invisible dimensions are efforts to peer into the hidden elements, and even the existential meaning of the universe. In the second half, he described his research and how he is trying to popularize the newest concepts and theories in science. He also sees parallels between spiritual ideas described by mystics throughout the ages and the efforts of mathematicians to map out extra dimensions which we cannot normally perceive and remarked that "all these new scientific concepts are the seedbed" for new spiritual conceptions.

White delved into the idea that dreams allow some of us access to a world unstuck from the seemingly linear nature of time. He described the experiences of British writer JW Dunne, his ideas about the dream state, and its possible power to let us see future events. He cited the revolutionary idea of Albert Einstein and how before him, "people thought of time as linear." Einstein proved that the experience of time depends on many factors, White said. He referred to the famous novel "Flatland" throughout the program and its example of two-dimensional beings who suddenly saw their world from a third dimension, and compared this to people who have had transcendent experiences and their newfound perspective. White concluded that "people have been trying to reach the transcendent as long there as there have been people on Earth."