Ethnobotanist and psychedelic pioneer Terence McKenna (1946-2000) spoke about his background in ethnobotany and shamanism as well as the nature of time, which he described as divided into a dynamic struggle between what he called "habit and novelty." Habit he defined as things that have been established and repeated, and novelty as anything that is new and "never before seen," and this was what drives what we call "time" forward. He said that this dynamic would accelerate quickly to some sort of end in the next few years, which Art compared to his own book "The Quickening," and which McKenna referred to as "Timewave Zero."

By 2012, the acceleration would not be sustainable, he predicted, and this matched up with a similar "end of time" idea indicated by the Mayan calendar, occurring on December 21, 2012. He also suggested that time travel would only be possible from the first instance that a time machine was invented, and that "tens of thousands" of time machines would then appear from the future to see how things began from that point.

McKenna delved into his research into psychedelic substances (particularly DMT) and their history, as well as their potential to recreate similar experiences to what many UFO abductees reported. He said the entities he encountered on his psychedelic trips were "upbeat and affirmative." He theorized that aliens "come through the human mind" and not in craft, and that our experience of them has been going on for thousands of years. In the third hour, McKenna began taking calls and questions. The last hour was taken up by Open Lines.